It appears that your Advanced Layout Builder conflicts with the basic handling of the toggle button of the meta boxes. The classes and aria-attributes aren’t properly set when Enfold is active. Loading below custom script in WP backend makes it work again.

THIS IS NOT A PERMANENT FIX – the bug is still in Enfold

$( “.metabox-location-normal button.handlediv[aria-expanded]” ).each(function( index ) {
$(this).on(‘click’ , function() {
$expanded = $(this).attr(‘aria-expanded’);
if( $expanded == ‘false’ ) {
$( this ).parents(‘.postbox’).removeClass(‘closed’);
$( this ).attr(‘aria-expanded’,’true’);
$( this ).find(‘.toggle-indicator’).attr(‘aria-hidden’,’false’);
} else {
$( this ).parents(‘.postbox’).addClass(‘closed’);
$( this ).attr(‘aria-expanded’,’false’);
$( this ).find(‘.toggle-indicator’).attr(‘aria-hidden’,’true’);
}
});
});